Surface-enhanced Raman spectroscopy of the filtrate portions of the blood serum samples of breast cancer patients obtained by using 30 kDa filtration device

Author：Hawa Hajab a,1 , Ayesha Anwar a,1 , Haq Nawaz a,* , Muhammad Irfan Majeed a,* , Najah Alwadie b,* , Sana Shabbir a , Arooj Amber a , Muhammad Idrees Jilani c , Hafiza Faiza Nargis a , Muhammad Zohaib d , Sidra Ismail e , Abida Kamal a , Muhammad Imran f

ABSTRACT：Raman spectroscopy is reliable tool for analyzing and exploring early disease diagnosis related to body fluids, such as blood serum, which contain low molecular weight fraction (LMWF) and high molecular weight fraction (HMWF) proteins. The disease biomarkers consist of LMWF which are dominated by HMWF hence their analysis is difficult. In this study, in order to overcome this issue, centrifugal filter devices of 30 kDa were used to obtain

Keywords:Breast cancer Blood serum Centrifugal filtration

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